Melior Discovery | The Melior Advantage

Melior's theraTRACE^SM indications discovery platform offers a cost-effective and efficient way to uncover new uses for drug-like molecules.

1. Multiplexed Models. theraTRACE^SM offers the ability to conduct multiple in vivo models on a single group of animals with a single compound without compromising the predictive quality of each model. In this way, theraTRACE^SM greatly accelerates the discovery process and is far more cost-effective than models run independently of one another. Melior has been able to effectively identify new indications for compounds using a fraction of the resources associated with traditional drug discovery and development methods.
2. "Systematic Serendipity." Melior's approach towards finding new uses for existing compounds does not rely on any preconceived notions commonly associated with hypothesis driven drug discovery strategies. These methods are typically forced to assume relationships between particular targets and diseases, which can greatly limit the scope of drug discovery efforts. In contrast, Melior's approach is rooted in evaluating a compound without bias across a wide range of gold-standard in vivo models of disease. Using this methodology, Melior has enjoyed repeated success in discovering non-obvious uses for compounds screened. Moreover, this strategy has identified target-disease associations that previously were not known.
3. Breadth. The unique theraTRACE^SM discovery platform has broad utility for identifying alternative therapeutic indications. This broad scope (over 30 standardized and validated models) maximizes the therapeutic potential of a partner's drug candidates and the likelihood of discovering new and alternative indications.
4. Speed. Melior can help partners to rapidly identify new development paths for failed, discontinued or otherwise de-prioritized drug candidates. In a matter of weeks, the theraTRACE^SM platform can comprehensively test a molecule for potential efficacy across a broad range of therapeutic areas.
5. Experience. The Melior team has extensive experience and expertise in pharmacology as well as in drug discovery and development. This extensive knowledge is reflected in the successful assembly and implementation of the theraTRACE^SM platform.