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Melior Discovery


          Melior Discovery in vivo pharmacology phenotypic screening

Melior Discovery has extensive capability in the area of in vivo pharmacology. 
Our management team has evaluated hundreds of compounds in thousands of experiments across dozens of animal models of human disease. Melior has applied this extensive know-how to pioneer theraTRACE®, a unique, high throughput in vivo pharmacology platform. We offer our expertise through contract research for individual animal models and engage in collaborations using our theraTRACE® platform.

 


in vivo pharmacology therapeutic areas

theratrace platform phenotypic screening


Our Drug Discovery Philosophy

 

Recent Studies Using Phenotypic Screening:


Phenotypic screening identifies Axl kinase as a nega...

Related Articles Phenotypic screening identifies Axl kinase as a negative regulator of an alveolar epithelial cell phenotype. Lab Invest. 2017 May 29;: Authors: Fujino N, Kubo H, Maciewicz RA Abstract Loss of epithelial barrier integrity is implic...

Small-molecule phenotypic screening with stem cells.

Related Articles Small-molecule phenotypic screening with stem cells. Nat Chem Biol. 2017 May 17;13(6):560-563 Authors: Ursu A, Schöler HR, Waldmann H PMID: 28514421 [PubMed - in process]




 

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