Dr. Christopher Lipinski
Dr. Lipinski is a medicinal chemist with more than 34 years of experience at Pfizer, Inc. In 2002 he retired from the highest scientific position in the worldwide Pfizer research organization (Senior Research Fellow) and now serves as a Drug-Like Properties consultant to Pfizer.
Dr. Lipinski is renowned for his “Rule of Five“; an algorithm for predicting drug compounds likely to show oral activity. His 2001 publication in “Advanced Drug Delivery Reviews“, where the “Rule of Five” first appears, is the most frequently cited medicinal chemistry paper in the last decade and is one of the most cited publications in the journal’s history. He was a recipient of the American Chemical Societies 2004 Medicinal Chemistry award.
Dr. Lipinski is a member of the Medicinal Chemistry section of the American Chemical Society, the American Association of Pharmaceutical Sciences, the Society for Biomolecular Screening and the European Federation of Pharmaceutical Sciences.
He serves on scientific advisory boards for the Global Alliance for Tuberculosis Drug Development, ASDI Biosciences, Advanced Chemistry Development Labs and the Matrical Company. Dr. Lipinski is a consultant for Symyx and the Hereditary Disease Foundation. He is a member of the editorial board of the Journal of Pharmaceutical Sciences, Current Drug Discovery Technology, the highlights advisory board of Nature Reviews Drug Discovery, as well as the advisory boards of several other journals.
He serves on the Conference Advisory Board for Cambridge Healthtech Institute. Since 1984, he has been an adjunct faculty member at Connecticut College in New London CT, and has over 180 publications and invited presentations and 17 issued US patents.
Dr. Lipinski received a B.Sc. degree in chemistry from San Francisco State College in 1965 and a Ph.D. in 1968 in physical organic chemistry from the University of California, Berkeley. He joined Pfizer in 1970 following a National Institutes of General Medical Sciences Postdoctoral Fellowship at the California Institute of Technology.