Discover how Melior’s unique phenotypic screening platforms can uncover the untapped value of your candidate therapeutic

Bioanalysis capabilities allow for quantitation of small molecule concentrations (e.g. drug levels) in biological samples (e.g. blood)  using HPLC with tandem mass spectroscopy (LC/MS/MS). Several samples types are handled including brain (whole, dissected brain regions, punches), whole blood or plasma, CSF, peripheral organs. 

Melior Discovery offers bioanalysis services in collaboration with our partner, Keystone Bioanalytical (North Wales, PA).  Melior has been working with Keystone since our inception in 2005. They are our chosen partner because of their high reliability, fast turn around, and reasonable cost.

Melior works with Keystone as a subcontracted service to provide the bioanalytical components of a study in a turnkey solution to our clients.  All bioanalytical data is integrated into our final study reports.


  • Pharmacokinetic studies
  • Drug exposure
  • Brain neurochemistry
  • Measurement of exogenous compounds
  • Measurement of drug metabolites 
This model is 1 of more than 60 models included in our theraTRACE® platform

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Contact us today for more information about our bespoke research models and to discuss how we can help you answer your unique research questions.

Frequently Asked Questions

Do you have the ability to perform the LC/MS/MS analysis?

Yes. We work closely with Keystone Bioanalytical who has the ability to analyze blood and other tissue samples.

Can bioanalysis be performed as part of a larger study?

Yes. Terminal collection of plasma, serum, whole blood, or other tissues can be performed and be sent for bioanalysis. Alternatively, blood or tissue can be collected at specific timepoints for analysis. Our scientists would be more than happy to discuss the feasibility of perform bioanalysis within a larger study.

Synonyms: PK, Pharmacodynamics, Pharmacokinetics