Histology

Discover how Melior’s unique phenotypic screening platforms can uncover the untapped value of your candidate therapeutic

Histology is an endpoint that is incorporated into many chronic studies such as NASH, fibrosis, the MPTP model and many others including many studies that evaluate biomarkers by immunohistochemistry.

Melior Discovery offers histology services in collaboration with our partner, CaresBio Laboratory (Westport, CT).  Melior has been working with CaresBio since 2017. They are our chosen partner because of their high reliability, fast turn around, and reasonable cost.  Moreover we are impressed by their expert pathology evaluation capability.

In addition to evaluation of tissue morphology using conventional staining methods such as hematoxylin and eosin (H&E), picrosirius red (PSR) and Masson’s trichrome (MT), CaresBio provides immunohistochemistry staining allowing for the evaluation of target or multiple biomarkers of interest.

Melior works with CaresBio as a subcontracted service to provide the histology components of a study in a turnkey solution to our clients.  All histology data is integrated into our final study reports.

Key Offerings: 

  • Histology evaluation
  • Immunohistochemistry staining
  • Pathology scoring (by blinded expert pathologist)
  • Cell counting
  • FACS analysis