Dr. Lindsey Mayes-Hopfinger

Director of Immunology and Inflammation

Dr. Lindsey Mayes-Hopfinger is the Director of Immunology & Inflammation at Melior. She has 7+ years’ experience studying inflammatory and cell death signaling pathways in vitro and in vivo.

Lindsey graduated from Thomas Jefferson University with a Ph.D. in Biochemistry and Molecular Pharmacology. During her graduate training, she focused on understanding regulatory mechanisms of the NLRP3 inflammasome utilizing primary mouse macrophages as well as peritonitis and colitis mouse models. In addition, she has characterized several cell death-mediated genetic knockout and conditional knockout mouse lines. Lindsey has extensive experience in in vitro cytotoxicity assays and cytokine ELISAs for blood, tissues, and cell culture supernatant.

In her time at Melior, Lindsey has served as the project coordinator on several influenza, pulmonary inflammation, LPS-induced systemic inflammation, acute pancreatitis, chronic pancreatitis, liver fibrosis, monocyte infiltration, and PK studies. Lindsey also serves as the Chair of Melior’s IACUC committee.

Lindsey prides herself on her attention to detail and her favorite part of the scientific process is designing new experimental models to solve complex problems. In her free time, she enjoys cooking and reading as well as spending time with friends and family.